mRNA treatment repairs mouse hearts to "near normal" after heart attack
By Michael Irving
June 19, 2022
Transcription factors delivered via mRNA have been shown to help regenerate heart cells after a heart attack
Researchers at the University of Houston have demonstrated a new technique for helping heart cells regenerate after a heart attack, using mRNA to return the cells to a stem-cell-like state. Tests in mice showed drastic improvements to heart function a month after a heart attack.
Unlike most tissues in the body, heart cells have a limited ability to regenerate after injury. That’s a big part of why heart attacks are so deadly – afterwards, non-beating scar tissue forms instead, which can lead to further attacks and eventually heart failure.