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Test the efficacy of oHSV for killing glioblastoma cancer cells.
Glioblastomas (GBM) are the most common tumors that arise from brain. Glioblastomas are usually highly malignant because the tumor cells reproduce quickly. The tumor contains mixed of cell types and they are supported by blood vessels. Glioblastoma is extremely difficult to treat by surgical resection or radiotherapy. oHSV has been investigated for the treatment of malignant tumor glioblastoma. The clinical studies have shown the safety of oHSV administration to the human brain. We focus on enhancing the therapeutic efficacy of oHSV for glioblastoma.
Potential Applications: Potential applications not yet defined for this project
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